About Lynside
Lynside® S. boulardii (CNCM I-3799) is a proprietary probiotic yeast designed to support digestive and immune health. Unlike many bacterial probiotics, it naturally survives gastric conditions and remains unaffected by antibiotics. This unique combination of resilience, stability and proven efficacy makes Lynside® an excellent choice for products targeting microbiota balance, digestive wellbeing and everyday immune support.
Lynside - application areas
Lynside® S. boulardii is particularly well suited to formulations focused on digestive resilience and microbiota recovery. Its natural resistance to antibiotics makes it ideal for products intended to support gut balance during or after antibiotic use. It can also be incorporated into solutions targeting traveller's digestive health, acute digestive disturbances and everyday digestive wellbeing.
Beyond gut health, Lynside® offers opportunities in immune support formulations due to its role in supporting intestinal immune responses. Excellent shelf stability and resistance to environmental stressors provide significant formulation flexibility, while reducing the need for specialised protection technologies. These characteristics make it suitable for capsules, sachets, stick packs and other consumer-friendly delivery formats.
Lynside Research
The health benefits of S. boulardii are among the most extensively documented within the probiotic yeast category. More than 70 clinical studies have investigated its effects on digestive and immune health. Research has demonstrated efficacy in helping reduce antibiotic-associated diarrhoea, traveller's diarrhoea and acute diarrhoeal episodes, while supporting restoration of a healthy microbiota balance.
Studies also suggest beneficial effects on immune function through modulation of intestinal immune responses. This extensive evidence base has helped establish S. boulardii as one of the most recognised and trusted probiotic yeast strains worldwide.
About ibSium
ibSium® (Saccharomyces cerevisiae CNCM I-3856) is a patented probiotic yeast developed to support digestive comfort and healthy bowel function. It was specifically selected for its ability to address common gastrointestinal symptoms linked to digestive imbalance. By helping restore intestinal comfort and regularity, ibSium® provides a targeted solution for consumers seeking clinically supported digestive wellness.
ibSium - application areas
ibSium® is ideally positioned for digestive comfort products that address common gastrointestinal concerns. It is particularly relevant for consumers experiencing abdominal discomfort, bloating and irregular bowel habits. The ingredient can be incorporated into formulations supporting the gut-brain axis, as digestive symptoms are often associated with functional bowel disorders and microbiota imbalance.
It also aligns with growing consumer demand for targeted solutions that move beyond general probiotic support. The strain's excellent stability at ambient temperatures simplifies formulation and distribution, while its compatibility with a variety of supplement formats provides flexibility for product developers. As digestive comfort remains one of the primary reasons consumers purchase probiotic products, ibSium® offers a highly relevant and differentiated proposition.
ibSium Research
ibSium® is supported by a robust clinical programme that includes four double-blind, placebo-controlled human studies and a meta-analysis. Research has demonstrated significant improvements in abdominal pain, bloating, stool consistency and overall quality of life.
Clinical data show that 63% of participants experienced meaningful reductions in abdominal pain, while bloating severity was reduced compared with placebo. Additional studies reported normalisation of bowel habits within four weeks. These findings have established ibSium® as a scientifically substantiated probiotic yeast for digestive comfort and gastrointestinal symptom management.
Frequently Asked Questions About Probiotic Yeasts
1. What makes probiotic yeasts different from bacterial probiotics?
Probiotic yeasts are living microorganisms that support gut health, but they differ significantly from bacterial probiotics. Their larger cell structure and unique biological properties allow them to remain stable under a wide range of manufacturing and storage conditions. They also work through different mechanisms, making them a valuable addition to modern microbiome formulations.
2. Can probiotic yeasts be taken alongside antibiotics?
Yes. One of the key advantages of probiotic yeasts is that they are naturally resistant to antibiotics. Unlike bacterial probiotics, they are not destroyed during antibiotic treatment. This makes them particularly useful for individuals seeking to maintain microbiota balance during and after a course of antibiotics.
3. Do probiotic yeasts survive stomach acid?
Probiotic yeasts are well known for their ability to survive the harsh conditions of the digestive tract. They can pass through stomach acid and bile salts while remaining viable. This helps ensure they reach the intestine, where they can exert their beneficial effects on digestive health and microbiota balance.
4. What health benefits do probiotic yeasts offer?
Clinical research has shown that specific probiotic yeast strains can support digestive health, intestinal comfort, microbiota balance and immune function. Emerging research also highlights the importance of a diverse microbiome in supporting broader areas of wellbeing, including the gut-brain and gut-skin axes.
5. Which probiotic yeast has been clinically studied for digestive comfort?
Not all probiotic yeasts deliver the same benefits. Some strains have been specifically researched for digestive comfort, helping to reduce symptoms such as bloating, abdominal discomfort and irregular bowel habits. ibSium® is supported by multiple human clinical studies demonstrating improvements in digestive comfort and overall quality of life, making it a targeted solution for consumers seeking relief from everyday gastrointestinal complaints.
6. Why combine Lynside® S. boulardii with ibSium®?
The two probiotic yeasts provide complementary benefits. Lynside® S. boulardii helps support microbiota balance, digestive resilience and immune function, while ibSium® is specifically researched for digestive comfort, including bloating, abdominal discomfort and bowel regularity. Together, they offer a comprehensive approach to gut health, addressing both microbiome support and everyday digestive wellbeing.
About Gnosis by Lesaffre
Gnosis by Lesaffre believe that good health must evolve from being reactive to being pre-emptive. By harnessing the power of micro-organisms and learning from nature’s intelligence, they create proactive, sustainable solutions that help people live stronger, longer and happier lives.
As an integrated part of the Lesaffre family, they are experts in biotransformation, tapping into over 170 years of expertise in fermentation and biotechnological innovation.