Levagen+®

Levagen+® is an award winning PEA ingredient, patented, with an enhanced-absorption form of PEA (Palmitoylethanolamide).

PEA is a naturally occurring fatty acid amide produced by the body in response to cellular stress and tissue injury, where it plays an important role in regulating inflammation and pain signalling.

 

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About Levagen+®

PEA is lipophilic (fat-loving) in nature, therefore has challenges with absorption and has limited format options (i.e. restricted to capsules and tablets). This limits brands and consumers to reap the full-benefits of this unique ingredient.

Saanroo® have developed Levagen+®, a cold-water dispersible version of PEA powered by LipiSperse® delivery technology.  This makes the ingredient suitable for a greater range of applications.

Levagen+® - 2026 award winner

Levagen+® was selected as the winning Healthspan ingredient category at the recent Nutraingredients Europe awards.  The judges recognised its strong clinical foundation, commercial traction, versatility across applications and clear innovation potential. As a cold-water-dispersible form of PEA, Levagen+® uses advanced LipiSperse® technology to support improved absorption and formulation flexibility.

This award further reinforces Levagen+® as a trusted, science-backed ingredient with proven relevance in today's market . We are proud to work with Saanroo and extend our warmest congratulations to their team on this well-deserved achievement.

Stop Press: Levagen+® was also the Innovation in Women's Health Category at the NutraIngredients USA Awards 2026.

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Levagen+® - applications

Levagen+ is supported by numerous clinical studies in the areas of:

Joint Health*
Sleep
Sports Recovery
Discomfort and Inflammation
‍Cognitive Health

Immune Health
Skin Health

*Levagen® demonstrated dose-dependent improvement (300mg & 600mg) in WOMAC scores* (discomfort, stiffness and function) compared to the placebo in the management of mild to moderate osteoarthritis (Steels et al. 2019).

‍Levagen® offers morning and evening joint ache reduction when compared to placebo over a 14 day period, suggesting that PEA may be a beneficial and effective treatment for joint pain.* (Briskey, et al. 2021)

Levagen+® Not Novel

Palmitoylethanolamide (PEA), the active ingredient in Levagen+®, has recently been listed in the EU Novel Food Catalogue as “not novel” for use in food supplements.

This means PEA has recognised evidence of use prior to May 1997 and therefore does not require novel food authorisation for supplement applications in the EU. For formulators and retailers, this provides valuable regulatory clarity around a highly researched bioactive lipid.

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Levagen+®: The Science

Levagen+® is a patented, enhanced form of palmitoylethanolamide (PEA), a naturally occurring lipid compound that has been extensively researched for its role in supporting the body's healthy inflammatory response and overall wellbeing. Unlike standard PEA, Levagen+® uses LipiSperse® technology to improve absorption, with studies demonstrating significantly higher bioavailability and faster uptake.

The ingredient has been evaluated in multiple human clinical trials, including randomised, double-blind, placebo-controlled studies investigating joint comfort, exercise recovery, sleep quality and immune health. This growing body of scientific research makes Levagen+® one of the most clinically studied and trusted forms of PEA available today.

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Lipisperse Technology

Levagen®+ is powered by LipiSperse® technology, developed by award-winning Pharmako Biotechnologies, to increase functionality and bioavailability of PEA for food and beverage applications.

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Our partner, Saanroo

Saanroo® botanicals are grown under the close supervision of their technical team and according to strict quality-assurance processes. For instance, their herbs are always dried in the shade, so they maintain their phytochemical content.

All their extracts comply with the California Prop-65 law for heavy metals and their single-herb standardized extracts are free from all known sources of contamination (including other herbs).